Human oocyte cryopreservation: new perspectives regarding oocyte survival

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Human oocyte cryopreservation.

The clinical role of oocyte cryopreservation in assisted reproduction, as an adjunct to sperm and embryo cryopreservation, has been comparatively slow to evolve as a consequence of theoretical concerns related to efficacy and safety. Basic biological studies in the 1990's alleviated many of these concerns leading to more widespread adoption of the technology. While a number of babies were born ...

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The technology so far applied clinically has been based directly on traditional human embryo cryopreservation protocols, and has produced relatively few offspring. Fortunately to date, no abnormalities have been reported from these pregnancies, regardless of the persistent concerns that freezing and thawing of mature oocytes may disrupt the meiotic spindle and thus increase the potential for an...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2001

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/16.3.411